Personal website of João Pedro de Magalhães
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"Success is never final." — Winston Churchill

In my latest paper, "Analyses of human-chimpanzee orthologous gene pairs to explore evolutionary hypotheses of aging," I show that surprisingly aging-associated genes tend to evolve slower and be more highly conserved between humans and chimpanzees than expected by chance. The goal of this work was to gather clues about the evolutionary mechanisms underlying the evolution of longevity in the human lineage. This paper was published in the Mechanisms of Ageing and Development (volume 128, issue 5-6, pages 355-364). It is available online.

In another recent paper, "An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts," I show that metabolic rates do not correlate with longevity. In contrast, growth rates and developmental schedules are strongly associated with adult lifespan. This work employed data from hundreds of species, the largest dataset ever used in such analysis. This paper was published in the Journal of Gerontology: Biological Sciences (volume 62, issue 2, pages 149-160). It is available online.

Previously, I also published an hypothesis paper, "Cells discover fire: Employing reactive oxygen species in development and consequences for aging," where I propose a new interpretation for the role of reactive oxygen in aging based on how they are employed in development and growth. This paper was published in Experimental Gerontology (volume 41, issue 1, pages 1-10). It is available online.

I've also recently published a book chapter, "Species Selection in Comparative Studies of Aging and Antiaging Research," where I debate how to compare aging between different species and propose a selection of species for comparative studies of aging. This review was published in the Handbook of Models for Human Aging, edited by P. Michael Conn and published by Elsevier Academic Press, pages 9-20.

For more information on the relevant papers I've published in the past as well as PDF reprints, please consult my list of selected publications.

I have an essay on my marketing strategy, which includes several links. Although it's more of a reference essay tailored to my activities, some might find it useful.

Thank you for visiting my website. I believe cooperation and networking are essential for success, so please feel free to contact me.